J Neuroimaging. 2010 Nov 17. doi: 10.1111/j.1552-6569.2010.00537.x. [Epub ahead
Acute White Matter Differences in the Fornix Following Mild Traumatic Brain Injury Using Diffusion Tensor Imaging.
Yallampalli R, Wilde EA, Bigler ED, McCauley SR, Hanten G, Troyanskaya M, Hunter JV, Chu Z, Li X, Levin HS.
From the Physical Medicine and Rehabilitation Alliance of Baylor College of Medicine and the University of Texas-Houston Medical School, Houston, TX (RY, EAW, SRMC, GH, MT, XL, HSL); Department of Neurology (EAW, SRMC); Department of Radiology (EAW, JVH, ZC); Department of Pediatrics, Baylor College of Medicine, Houston, TX (SRMC, HSL); Department of Pediatric Radiology, Texas Children’s Hospital, Houston, TX (EAW, JVH, ZC); Michael E. DeBakey Veterens’ Affairs Medical Center (EAW, SRMC, MT, HSL); Department of Psychology, University of Houston, Houston, TX (RY); Department of Psychology and Neuroscience Center, Brigham Young University, Provo, UT (EDB); Department of Psychiatry and the Utah Brain Institute, University of Utah, Salt Lake City, UT (EDB).
The integrity of the fornix using diffusion tensor imaging (DTI) in adolescent participants with acute mild traumatic brain injury (mTBI) compared to a demographically matched control group was examined. Fractional anisotropy (FA) in the fornix was elevated in the mild traumatic brain injured group. Performance on the Automated Neuropsychological Assessment Metrics (ANAM) was lower in the group with mTBI. A relation was found between lower performance on cognitive tasks and higher FA. The potential role of fornix injury as a basis of memory and processing speed deficits in mTBI is discussed.
© 2010 by the American Society of Neuroimaging.
PMID: 21988147 [PubMed – as supplied by publisher]